Vered Stearns Selected Research

exemestane (Aromasin)

10/2022	Genome-wide association study of aromatase inhibitor discontinuation due to musculoskeletal symptoms.
1/2021	Genome-wide association study of letrozole plasma concentrations identifies non-exonic variants that may affect CYP2A6 metabolic activity.
8/2019	Prospective evaluation of finger two-point discrimination and carpal tunnel syndrome among women with breast cancer receiving adjuvant aromatase inhibitor therapy.
6/2019	Exemestane may be less detrimental than letrozole to bone health in women homozygous for the UGT2B17*2 gene deletion.
1/2019	Effects of SLCO1B1 polymorphisms on plasma estrogen concentrations in women with breast cancer receiving aromatase inhibitors exemestane and letrozole.
7/2018	Tailoring Adjuvant Endocrine Therapy for Premenopausal Breast Cancer.
10/2017	Variable aromatase inhibitor plasma concentrations do not correlate with circulating estrogen concentrations in post-menopausal breast cancer patients.
7/2017	Prospective assessment of patient-reported outcomes and estradiol and drug concentrations in patients experiencing toxicity from adjuvant aromatase inhibitors.
1/2017	Effects of exemestane and letrozole therapy on plasma concentrations of estrogens in a randomized trial of postmenopausal women with breast cancer.
12/2016	Genetic Polymorphisms in the Long Noncoding RNA MIR2052HG Offer a Pharmacogenomic Basis for the Response of Breast Cancer Patients to Aromatase Inhibitor Therapy.

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Vered Stearns Research Topics

Disease

156	Breast Neoplasms (Breast Cancer) 10/2022 - 04/2002
78	Neoplasms (Cancer) 01/2022 - 04/2002
20	Hot Flashes 01/2011 - 04/2002
11	Triple Negative Breast Neoplasms 01/2022 - 08/2009
9	Pain (Aches) 10/2022 - 09/2008
8	Pathologic Complete Response 10/2021 - 02/2010
5	Cardiovascular Diseases (Cardiovascular Disease) 03/2016 - 05/2003
4	Neoplasm Metastasis (Metastasis) 01/2022 - 07/2013
4	Weight Loss (Weight Reduction) 01/2022 - 01/2017
3	Disease Progression 01/2021 - 01/2018
3	Carcinogenesis 01/2020 - 07/2006
2	Neutropenia 01/2022 - 06/2009
2	Brain Neoplasms (Brain Tumor) 04/2021 - 08/2014
2	Noninfiltrating Intraductal Carcinoma (DCIS) 01/2019 - 03/2009
2	Cardiotoxicity 01/2018 - 02/2010
2	Syndrome (Syndromes) 01/2016 - 08/2014
2	Hypersensitivity (Allergy) 10/2014 - 12/2009
2	Osteoporosis 04/2013 - 03/2011
2	Hematologic Neoplasms (Hematological Malignancy) 12/2012 - 03/2012
2	Arthralgia (Joint Pain) 03/2011 - 09/2010
2	Prostatic Neoplasms (Prostate Cancer) 11/2009 - 07/2004

Drug/Important Bio-Agent (IBA)

51	Hormones (Hormone)IBA 10/2022 - 06/2003
33	Aromatase InhibitorsIBA 10/2022 - 07/2006
27	Tamoxifen FDA LinkGeneric 07/2018 - 12/2003
26	Biomarkers (Surrogate Marker)IBA 01/2022 - 11/2004
23	exemestane (Aromasin)FDA Link 10/2022 - 09/2008
20	Letrozole (Femara)FDA LinkGeneric 10/2022 - 07/2006
19	Estrogen ReceptorsIBA 01/2022 - 12/2008
16	Estrogens (Estrogen)FDA Link 03/2021 - 05/2003
12	Pharmaceutical PreparationsIBA 10/2017 - 07/2006
11	Cytochrome P-450 CYP2D6 (CYP2D6)IBA 03/2012 - 12/2003
10	human ERBB2 proteinIBA 01/2022 - 01/2015
10	DNA (Deoxyribonucleic Acid)IBA 11/2017 - 03/2012
8	Anastrozole (Arimidex)FDA LinkGeneric 10/2017 - 12/2010
8	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2016 - 01/2003
7	Antidepressive Agents (Antidepressants)IBA 01/2011 - 05/2003
6	Progesterone Receptors (Progesterone Receptor)IBA 10/2017 - 11/2009
6	Cyclophosphamide (Cytoxan)FDA LinkGeneric 10/2014 - 03/2004
5	Histone Deacetylase InhibitorsIBA 01/2022 - 01/2015
5	palbociclibIBA 01/2022 - 01/2018
5	Trastuzumab (Herceptin)FDA Link 10/2021 - 02/2010
5	Gabapentin (Neurontin)FDA LinkGeneric 09/2009 - 05/2003
5	Serotonin (5 Hydroxytryptamine)IBA 01/2006 - 04/2002
5	Paroxetine (Paxil)FDA LinkGeneric 01/2006 - 05/2003
4	taxaneIBA 10/2022 - 08/2009
4	entinostat (MS 275)IBA 01/2022 - 01/2016
4	Paclitaxel (Taxol)FDA LinkGeneric 01/2021 - 01/2003
4	PlatinumIBA 01/2021 - 06/2015
4	VaccinesIBA 10/2020 - 03/2004
4	Proteins (Proteins, Gene)FDA Link 01/2020 - 01/2003
4	ametantrone (HAQ)IBA 07/2017 - 09/2008
4	Raloxifene Hydrochloride (Evista)FDA Link 09/2013 - 07/2006
4	SodiumIBA 07/2011 - 12/2004
3	pertuzumabIBA 10/2021 - 01/2018
3	Carboplatin (JM8)FDA LinkGeneric 01/2021 - 10/2011
3	CytokinesIBA 01/2020 - 02/2014
3	LipidsIBA 01/2020 - 12/2012
3	Vorinostat FDA Link 01/2018 - 07/2013
3	MethyltransferasesIBA 06/2017 - 12/2012
3	Estradiol (Delestrogen)FDA LinkGeneric 01/2017 - 06/2003
3	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 10/2014 - 03/2004
3	AndrogensIBA 10/2013 - 07/2004
3	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 09/2013 - 05/2006
3	Docetaxel (Taxotere)FDA Link 09/2012 - 06/2006
3	EnzymesIBA 01/2011 - 01/2005
3	Selective Estrogen Receptor Modulators (SERM)IBA 01/2011 - 07/2006
3	Selective Serotonin Reuptake Inhibitors (Serotonin Reuptake Inhibitors)IBA 01/2006 - 12/2003
2	Immune Checkpoint InhibitorsIBA 01/2022 - 01/2020
2	Cyclin-Dependent Kinases (cdk Proteins)IBA 01/2022 - 12/2018
2	RNA (Ribonucleic Acid)IBA 01/2022 - 05/2002
2	ErbB Receptors (EGF Receptor)IBA 10/2019 - 01/2015
2	Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link 01/2019 - 01/2015
2	Methylnitrosourea (N-Methyl-N-nitrosourea)IBA 01/2019 - 10/2011
2	Estrone FDA Link 01/2017 - 02/2012
2	estrone sulfate (Evex)FDA Link 01/2017 - 02/2012
2	Transaminases (Aminotransferases)IBA 07/2015 - 05/2011
2	Albumin-Bound Paclitaxel FDA Link 01/2015 - 10/2011
2	salicylhydroxamic acid (SHAM)IBA 02/2014 - 02/2013
2	AnthracyclinesIBA 05/2013 - 08/2009
2	liposomal doxorubicin (Doxil)FDA Link 08/2012 - 10/2011
2	1-dodecylpyridoxal (PLD)IBA 08/2012 - 10/2011
2	4-hydroxy-N-desmethyltamoxifenIBA 03/2012 - 07/2006
2	Simvastatin (Zocor)FDA LinkGeneric 02/2012 - 01/2012
2	Protons (Proton)IBA 07/2011 - 12/2004
2	trans-sodium crocetinate (crocetin)IBA 07/2011 - 12/2007
2	pegfilgrastim (Neulasta)FDA Link 06/2006 - 05/2006
2	Serotonin and Noradrenaline Reuptake InhibitorsIBA 01/2006 - 07/2004
2	Progestins (Progestagens)IBA 01/2006 - 06/2003

Therapy/Procedure

93	Therapeutics 04/2022 - 04/2002
30	Drug Therapy (Chemotherapy) 01/2022 - 01/2003
11	Neoadjuvant Therapy 10/2020 - 04/2002
6	Radiotherapy 01/2022 - 04/2002
6	Chemoprevention 09/2013 - 11/2004
4	Adjuvant Chemotherapy 12/2016 - 05/2006
4	Hypnosis (Mesmerism) 07/2010 - 07/2004
3	Segmental Mastectomy (Lumpectomy) 01/2022 - 04/2002
3	Immunotherapy 01/2022 - 12/2009
3	Precision Medicine 10/2021 - 01/2017
2	Caloric Restriction 01/2022 - 01/2017
2	Duration of Therapy 10/2019 - 07/2006